Overview
This case study highlights how continuous processing was used to accurately disperse low-percentage liquid actives into excipients to produce granulated material suitable for tablet pressing.
Challenges
- Accurately dosing liquid active ingredients at very low concentrations.
- Achieving uniform dispersion without excess moisture.
- Meeting particle size and compactibility requirements.
Solutions
A Continuous Processor generated a steady stream of well-dispersed granules using minimal moisture. The enclosed mixing chamber minimized dust while maintaining tight control over dispersion.
Results
- Uniform granulated product ready for tablet pressing.
- No additional drying required.
- Reduced processing steps and material loss.
- Improved cleanliness with minimal dust generation.
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